Our service offer

The whole-blood loop assay is an important part of preclinical safety evaluation with the aim to predict drug-related side effects and minimize risks in the first-in-man clinical studies. Advanced characterization services are paired with immunological know-how and expertise. The assay setup is designed together with you and your team to enhance data output. The whole-blood loop assay is applicable in the drug discovery and development process from screening of antibody leads to early clinical development. It is also suitable for biosimilars, bi-specific antibodies (BiTEs), as well as CAR modified T cells that are approaching the market.

We provide a validated, cost effective and powerful assay for early candidate selection that:

  • Indicates in vivo human effects early in the candidate selection process
  • Predicts effects/adverse events without biohazard
  • Reduces and refines animal studies
  • Points out immunological biomarkers to improve clinical trial design
  • Provides data to be used in discussions with Regulatory Bodies to improve the understanding of your lead candidate and your clinical trial design

If you are interested in our services, we are happy to hear from you:

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