Unique whole blood analysis
- Fresh circulating human whole blood
- Plasma, cells and platelets are present as well as cascade systems
- The drug is infused into the circulating blood
- The drug and blood are allowed to interact in a dymanic manner
- Multiple read outs from each test condition
- Results are delivered in flexible scientific reports
When a biological drug is administered into the human circulation, it can react with different components of the blood – in both anticipated and unexpected ways.
Blood is a complex system in which both cells and plasma components play significant roles. Even the blood’s movement is important for binding and other interactions. Immuneed’s services build on our specially developed platform ID.Flow, which uses fresh, circulating human blood and leaves all cells and systems intact. By using blood that is gently collected and kept in constant circulation, ID.Flow offers a physiologically relevant testing environment for understanding infusion reactions, immune-modulating properties, and the effect of your drug
Benefits of ID.Flow
Multiple read outs
ID.Flow is a powerful alternative to traditional preclinical methods. It allows simultaneous study of safety and function, thereby providing multiple read-outs from a single sample - cutting time and cost.
Fresh whole blood
ID.Flow leaves all blood components intact, from the plasma and cells to the complement proteins and endogenous antibodies. Likewise, the blood’s complement and coagulation cascade systems remain fully active, so that no response goes unmissed – even if they are unexpected.
High predictive value
The absence of high background interference ensures exceptional sensitivity that aids in the prediction of clinically relevant responses.